The neurotoxic effects of continuous cocaine and amphetamine in Habenula: implications for the substrates of psychosis.

The neurotoxic effects of continuous cocaine and amphetamine in Habenula: implications for the substrates of psychosis.
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连续可卡因和安非他明对缰核的神经毒性作用:对精神病基质的影响。

DOI:
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发表时间:
1996
期刊:
NIDA research monograph
影响因子:
--
通讯作者:
G. Sulur
G. Sulur
中科院分区:
--
文献类型:
--
作者:
G. Ellison;S. Irwin;A. Keys;K. Noguchi;G. Sulur

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The experiments described in this chapter have grown out of attempts to develop animal models of psychosis, especially schizophrenia. Because of the difficulties inherent in identifying and quantifying hallucinatory episodes in nonhumans, it is necessary to develop thirdorder models of psychoses when using animals. Thus, there are endogeneous psychotic states in humans such as occur in schizophrenia and other dementias, there are certain drug-induced states in humans that can be indistinguish-able in many aspects from endogeneous psychoses, and finally there are attempts to replicate similar drug-induced states in animals and thereby clarify the altered neural mechanisms that underlie these abnormal states.
与 D-苯丙胺相比,可卡因不会引起 Long-Evans 大鼠新纹状体和无颗粒额叶皮层的轴突变性。
DOI: 10.1016/0024-3205(88)90307-4
发表时间: 1988
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DOI: --
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发表时间: 1987
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DOI: 10.1037//0735-7044.106.5.853
发表时间: 1992
影响因子: 1.9
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