Young adult follow-up of hyperactive children: Self-reported psychiatric disorders, comorbidity, and the role of childhood conduct problems and teen CD
Young adult follow-up of hyperactive children: Self-reported psychiatric disorders, comorbidity, and the role of childhood conduct problems and teen CD
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DOI：
10.1023/a:1019864813776
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发表时间：
2002-10-01
影响因子：
3.6
通讯作者：
Fletcher, K
中科院分区：
文献类型：
--
作者：
Fischer, M;Barkley, RA;Fletcher, K
我们报告了在年轻成人随访（平均年龄20-21岁; 13年以上随访）时出现的精神疾病，以及大样本多动（H; N = 147）和社区对照（CC; N = 71）儿童中的合并症。H组发生任何非药物性精神疾病的风险显著高于CC组（59% vs. 36%）。在随访时，H组中符合ADHD（5%）、重度抑郁症（26%）、表演型（12%）、反社会型（21%）、被动攻击型（18%）和边缘型人格障碍（14%）标准的患者多于CC组。儿童期行为问题的严重性导致被动攻击型、边缘型和反社会型人格障碍的风险。但在控制了青少年行为障碍（CD）的严重程度后，它只影响反社会人格的风险，这也有助于这三种疾病的风险。对这些障碍的共病检查表明，边缘型或反社会型人格障碍的存在显着增加了重度抑郁症和其他显着人格障碍的风险。在高中期间和高中毕业后，多动组中接受过各种形式心理健康治疗的人比对照组多。结果表明，多动儿童在年轻的成年期至少有1种非药物性疾病，主要是重度抑郁症和几种人格障碍的显着风险，这种风险在很大程度上介导的CD在青春期的严重程度。
We report on the psychiatric disorders present at young adult follow-up (Mean age 20-21 years; 13 + year follow-up) and the comorbidity among them for a large sample of hyperactive (H; N = 147) and community control (CC; N = 71) children. The H group had a significantly higher risk for any nondrug psychiatric disorders than the CC group (59% vs. 36%). More of the H group met criteria for ADHD (5%); major depressive disorder (26%); and histrionic (12%), antisocial (21%), passive-aggressive (18%), and borderline personality disorders (14%) at follow-up than the CC group. Severity of childhood conduct problems contributed to the risk for passive-aggressive, borderline, and antisocial personality disorders. But it only affected risk for antisocial personality after controlling for severity of teen conduct disorder (CD), which also contributed to the risk for these same 3 disorders. Examination for comorbidity among these disorders indicated that presence of either borderline or antisocial personality disorder significantly increased the risk for major depression and the other significant personality disorders. More of the hyperactive group had received various forms of mental health treatment during and since leaving high school than the control group. Results suggest that hyperactive children are at significant risk for at least 1 nondrug disorder in young adulthood, principally major depression and several personality disorders, and that this risk is largely mediated by severity of CD at adolescence.