Thirteen-megahertz ultrasound probe: its role in diagnosing localized scleroderma
Thirteen-megahertz ultrasound probe: its role in diagnosing localized scleroderma
复制标题
DOI：
10.1046/j.1365-2133.2003.05289.x
复制
发表时间：
2003-04-01
影响因子：
10.3
通讯作者：
Radier, C
中科院分区：
文献类型：
--
作者：
Cosnes, A;Anglade, MC;Radier, C
背景 超声成像已被证明可用于评估全身性和局限性硬皮病 (LS)。但其特异性和敏感性尚未研究。 目的 明确 LS 的形态学超声诊断标准，并用 13 MHz 超声探头测试其敏感性和特异性。 方法 对连续 26 例 LS 患者的 40 个斑块进行检查，并与 16 例鉴别诊断 LS 的皮肤病患者的 17 个对照斑块进行盲法比较。数据还与正常对照组进行了比较。第一次检查后 12-18 个月对 5 名患者进行了重新评估。结果超声检查显示出特征性的密集图像，类似于扁平的“溜溜球”。真皮起伏、组织混乱、厚度减少和皮下高回声带增厚，以及“溜溜球”图像对 LS 具有高敏感性和高特异性。当这五种体征中至少出现四种时，LS 的敏感性为 92%，特异性为 100%。结论 13 兆赫超声是诊断 LS 的重要工具。形态学超声诊断标准具有较高的特异性和敏感性。
Background Ultrasound imaging has been shown to be useful for the evaluation of systemic and localized scleroderma (LS). However, its specificity and sensitivity have not been studied.Objectives To define morphological ultrasound diagnostic criteria in LS and to test their sensitivity and specificity with a 13-MHz ultrasound probe.Methods Forty plaques in 26 consecutive patients with LS were examined and compared blindly with 17 control plaques in 16 patients with skin diseases where LS was in the differential diagnosis. Data were also compared with a normal control group. Five patients were re-evaluated 12-18 months after the first examination.Results Ultrasound examination disclosed a characteristic dense image resembling a flattened 'yo-yo'. Undulations of the dermis, disorganization, loss of thickness and thickened hyperechoic bands in the hypodermis, and the 'yo-yo' image had a high sensitivity and a high specificity for LS. A 92% sensitivity and a 100% specificity for LS were found when at least four of these five signs were present.Conclusions Thirteen-megahertz ultrasound is a valuable tool for diagnosing LS. Morphological ultrasound diagnostic criteria had a high specificity and a high sensitivity.