Does patient age affect the PPV3 of ACR BI-RADS Ultrasound categories 4 and 5 in the diagnostic setting?
Does patient age affect the PPV3 of ACR BI-RADS Ultrasound categories 4 and 5 in the diagnostic setting?
复制标题
患者年龄是否会影响诊断环境中 ACR BI-RADS 超声类别 4 和 5 的 PPV3？
DOI：
10.1007/s00330-017-5203-3
复制
发表时间：
2018-06-01
影响因子：
5.9
通讯作者：
Su, Fengxi
中科院分区：
文献类型：
--
作者：
Hu, Yue;Yang, Yaping;Su, Fengxi
目的：计算不同年龄组中美国放射学会乳腺影像报告和数据系统 (ACR BI-RADS US) 图集第 4 类和第 5 类超声部分进行的活检 (PPV3) 的阳性预测值，并确定患者年龄是否影响每个类别的 PPV3 在乳腺病变的诊断中的作用。方法：我们识别了 2,433 名 ACR BI-RADS US 4 类和 5 类患者 2,433 名女性中具有已知病理诊断的病变。患者被分为三个年龄组（<35岁、35-50岁和>50岁）。根据病理诊断结果计算各年龄组各类别与年龄相关的PPV3，并采用卡方检验进行比较。结果：各类别总体PPV3均在ACR 2013年提供的参考范围内。4类病变患者PPV3随着年龄的增加逐渐升高。在最古老的4A和4B亚类病变组中，PPV3接近或超过参考值。结论：根据最新版ACR BI-RADS US在诊断环境中，PPV3和年龄在4类病变患者中显着相关。在指定最终评估类别时，应更加密切地关注老年患者。要点：• 在患有 4 类病变的患者中，恶性肿瘤的可能性与年龄相关。 • 对于5 类病变的患者，这种关联并不明确。 • 在应用ACR BI-RADS US 时应更加关注老年患者。
Objectives:To calculate the positive predictive value of biopsies performed (PPV3) of the Ultrasound section of the American College of Radiology Breast Imaging Reporting and Data System (ACR BI-RADS US) atlas categories 4 and 5 in different age groups and to determine whether patient age influences the PPV3of each category in the diagnosis of breast lesions.Methods:We identified 2,433 ACR BI-RADS US categories 4 and 5 lesions with a known pathological diagnosis in 2,433 women. The patients were classified into three age groups (<35, 35-50, and >50 years). The age-related PPV3of each category in the three age groups were calculated based on the pathological diagnoses and compared using the chi-squared test.Results:The overall PPV3of each category was within the reference range provided by the ACR in 2013. PPV3gradually increased with increasing age in patients with category 4 lesions. PPV3in the oldest group with subcategories 4A and 4B lesions were close to or exceeded the reference values.Conclusions:PPV3and age were significantly associated in patients with category 4 lesions according to the newest edition of ACR BI-RADS US in the diagnostic setting. Closer attention should be given to older patients when assigning a final assessment category.Key points:• In patients with category 4 lesions , the likelihood of malignancy is associated with age. • In patients with category 5 lesions, the association is not definite. • Closer attention should be given to older patients in applying the ACR BI-RADS US.