CASE-CONTROL STUDY ON CARDIOVASCULAR FUNCTION IN FEMALES WITH A HISTORY OF HEAVY EXPOSURE TO CADMIUM
CASE-CONTROL STUDY ON CARDIOVASCULAR FUNCTION IN FEMALES WITH A HISTORY OF HEAVY EXPOSURE TO CADMIUM
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DOI：
10.1007/bf01623539
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发表时间：
1986-04-01
影响因子：
2.7
通讯作者：
KAWANO, S
中科院分区：
文献类型：
--
作者：
KAGAMIMORI, S;WATANABE, M;KAWANO, S
研究对象为26名平均年龄为75.3 ± 7.4岁的女性，她们在第一次和第二次世界大战期间通过摄入镉污染的水、大米和鱼而高度暴露于镉，随后从镉污染地区收获的农产品中轻度暴露于镉，并正在接受慢性镉诱导疾病的治疗。与健康对照组相比，这些受试者血液中的红细胞计数和血红蛋白含量显着降低，收缩压和舒张压显着降低。与慢性镉病的症状更经常从缺血性变化的心脏比对照组。低频率可能是由于低血压。有一种趋势，为主题与慢性镉疾病发展障碍的传导系统的心脏，测量使用心电图。
Cardiovascular function was investigated in 26 women, mean 75.3 ± 7.4 years old who were considered to have had high exposure to cadmium through ingesting contaminated water, rice and fish around World War I and II, and to subsequent low-grade exposure from agricultural produce harvested from Cd-polluted areas and were being treated for chronic Cd-induced disorders. These subjects had a significantly lower erythrocyte count and haemoglobin content in blood and significantly lower systolic and diastolic blood pressure than did healthy controls. Sybjects with chronic Cd disease were more often free from ischaemic changes of the heart than the controls. Low frequency may be attributed to low blood pressure. There was a tendency for subjects with chronic Cd disease to develop disorders of the conduction system of the heart, measured using an electrocardiogram.