Indicative findings of pancreatic cancer in prediagnostic CT
Indicative findings of pancreatic cancer in prediagnostic CT
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DOI:
10.1007/s00330-009-1422-6
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发表时间:
2009-10-01
影响因子:
5.9
通讯作者:
Lim, Joon Seok
中科院分区:
文献类型:
--
作者:
Ahn, Sung Soo;Kim, Myeong-Jin;Lim, Joon Seok
We examined 20 prediagnostic CTs from 16 patients for whom the diagnosis of pancreatic cancer was delayed until full diagnostic CT was performed. Three radiologists independently reviewed the prediagnostic CTs along with 50 CTs of control subjects, including patients without pancreatic disease (n=38) or with chronic pancreatitis without calcification visible on CT (n=12). The reviewers recorded the presence of biliary or pancreatic ductal dilation, interruption of the pancreatic duct, distal parenchymal atrophy, contour abnormality and focal hypoattenuation. Frequency, sensitivity and specificity of the significant findings were calculated. Logistic regression analysis was performed. Findings indicative of pancreatic cancer were seen on 85% (17/20) of the prediagnostic CTs. Patients with pancreatic cancer were significantly (p