Laryngeal paralysis in a Rottweiler with neuroaxonal dystrophy

Laryngeal paralysis in a Rottweiler with neuroaxonal dystrophy
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DOI:
10.1111/j.1751-0813.1997.tb15650.x
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发表时间:
1997-11-01
影响因子:
1.1
通讯作者:
Clarke, RE
Clarke, RE
中科院分区:
农林科学4区
文献类型:
--
作者:
Bennnett, PF;Clarke, RE

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病例报告杓状软骨6和环甲肌活检采取了所有喉肌肉明显萎缩。术后期间喘鸣、呼吸困难和咳嗽不太严重,但犬的呼吸在任何阶段都不完全正常。肌肉活检的组织学检查显示活动性肌肉变性,结缔组织过多,再生不足。犬恢复良好,在接下来的3周内表现出良好的运动耐受性,呼吸音增加最小。在这些访视中观察到犬的后肢步态异常。有时,腿上升有一些困难,狗有一个兔子跳跃后肢步态时,运行。神经系统检查未发现本体感觉或其他神经功能缺损。手术后四周,这只狗在锻炼时出现虚脱。主人报告说,它表现出后肢无力,不自觉地排尿和口吐白沫。在塌陷前约10天,呼吸噪音增加。就诊时,该犬活泼警觉,除轻微咳嗽和吸气性喘鸣外无异常。无法看到喉部。初步诊断为杓状软骨偏侧化失败和运动诱发的晕厥发作。由于狗主人不想让狗住院,他们被指示严格限制和密切观察狗。12小时后,这只狗再次出现,当它再次崩溃时,
Case reports arytenoid6 and a biopsy of the cricothyroid muscle was taken as all laryngeal musculature was markedly atrophied. The stridor, dyspnoea and cough were less severe in the postoperative period, but at no stage was the dog’s respiration totally normal. Histological examination of the muscle biopsy showed active muscle degeneration, with excess connective tissue and scant regeneration. The dog recovered well and over the following 3 weeks showed good exercise tolerance with minimal increase in respiratory sounds. It was noted at these visits that the dog’s hindlimb gait was abnormal. At times the leg rised with some difficulty and the dog had a bunny-hopping hindlimb gait when running. No proprioceptive or other neurological deficits could be elicited on neurological examination. Four weeks after surgery the dog was presented after it had suffered a collapse while exercising. The owners reported that it had displayed hindlimb weakness, involuntarily voided urine and frothed at the mouth. An increase in respiratory noise for about 10 days prior to the collapse had been noticed. At presentation the dog was bright and alert, with no abnormalities except a soft cough and inspiratory stridor. It was not possible to visualise the larynx. A tentative diagnosis of a failure of the arytenoid lateralisation and a syncopal episode induced by the exercise was made. Because the owners did not wish to hospitalise the dog, they were instructed to keep it strictly confined and under close observation. The dog was re-presented 12 hours later, when it had again collapsed, this