Nasopharyngeal Carcinoma
Nasopharyngeal Carcinoma
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DOI：
10.1007/s12105-012-0333-z
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发表时间：
2012-09-01
影响因子：
2.1
通讯作者：
Castle, James T.
中科院分区：
文献类型：
--
作者：
Carle, Laura N.;Ko, Charles C.;Castle, James T.
鼻咽癌（NPC）在世界大部分地区罕见，但在中国南部、东南亚和北非更为常见。人们一度认为鼻咽癌最常发生在香港和台湾，那里每40名男性中就有1人在75岁之前患上鼻咽癌。有趣的是，人们注意到，来自这些地区的移民也会患上鼻咽癌。然而，这些趋势似乎正在略有变化。马来西亚和新加坡部分地区的利率正日益高于香港。美国和欧洲的年发病率约为每10万人中有1人，男女患病率为2:1，发病率高峰年龄在60岁左右。
DiscussionNasopharyngeal carcinoma (NPC) is rare in most parts of the world, but is more common in southern China, Southeast Asia, and North Africa. Once thought to occur most frequently in Hong Kong and Taiwan where 1 in 40 men develop NPC before the age of 75, NPC is also, interestingly, noted to arise in immigrants from these areas [1]. However, these trends appear to be changing slightly. Parts of Malaysia and Singapore are demonstrating increasingly higher rates than that seen in Hong Kong [6]. The annual incidence in the United States and Europe is approximately 1 per 100,000 of the population and shows a 2: 1 male: female prevalence with a peak age of incidence in the sixth decade [2].