A 16-microcantilever array sensing system for the rapid and simultaneous detection of analyte
A 16-microcantilever array sensing system for the rapid and simultaneous detection of analyte
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DOI：
10.1016/j.snb.2016.06.049
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发表时间：
2016-12-01
影响因子：
8.4
通讯作者：
Beaulieu, L. Y.
中科院分区：
文献类型：
--
作者：
Alodhayb, Abdullah;Rahman, S. M. Saydur;Beaulieu, L. Y.
我们报告了一种新的16微悬臂梁传感器系统进行传感实验，在液体或气体。该系统使用两个8微悬臂梁阵列，是在一个传感器单元举行。通过在微悬臂上振荡两个聚焦光束来监测微悬臂的偏转，使得一次仅照射一个微悬臂，并且每个微悬臂大约每秒照射一次。使用电动平移台移动光束。反射光束由双轴光敏检测器（PSD）检测，产生一系列两个八峰形图案。来自PSD和平移台的原始数据用于将来自每个阵列的峰形图案一个叠在另一个的顶部上，使得可以从每个峰的高度变化获得杠杆的偏转。数据的稳定性被认为是高度依赖于翻译阶段的速度。当平移台在0.5和1 mm/s之间操作时，发现以表面应力为单位的每个微悬臂梁的偏转在阵列之间是高度可再现的和一致的。作为目的验证应用，该系统用于使用不同的杯[4]芳烃基传感层检测Ca 2+、Sr 2+和Cs+离子。所获得的结果被认为是可重复的，并完全一致的结果，使用一个典型的两个单一的微悬臂梁传感器设置。(C)2016爱思唯尔B. V.保留所有权利。
We report on a new 16 microcantilever sensor system for performing sensing experiments in liquid or gas. The system uses two 8-microcantilever arrays that are held in a sensor cell. The microcantilever deflections are monitored by oscillating two focused optical beams over the microcantilevers such that only one microcantilever is illuminated at one time and each microcantilever is illuminated approximately once per second. The optical beams are moved using a motorized translation stage. The reflected optical beams are detected by a two-axis photo-sensitive detector (PSD) producing a series of two eight peak shaped patterns. The raw data from both the PSD and the translation stage are used to fold the peak shaped patterns from each array one on top of the other so that the deflection of the cantilevers can be obtained from the change in height of each peak. The stability of the data was found to be highly dependent on the speed of the translation stage. When the translation stage was operated between 0.5 and 1 mm/s, the deflection of each microcantilever in units of surface stress was found to be highly reproducible and consistent between arrays. As a proof-of-purpose application, the system was used to detect Ca2+, Sr2+ and Cs+ ions using different calix[4] arene-based sensing layers. The results obtained were found to be reproducible and completely consistent with results obtained using a typical two single microcantilever sensor set-up. (C) 2016 Elsevier B.V. All rights reserved.