JAW CYSTS WITH ORTHOKERATINIZATION - ANALYSIS OF 12 CASES
JAW CYSTS WITH ORTHOKERATINIZATION - ANALYSIS OF 12 CASES
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DOI：
10.1111/j.1600-0714.1993.tb00117.x
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发表时间：
1993-01-01
影响因子：
3.3
通讯作者：
TANIMOTO, K
中科院分区：
文献类型：
--
作者：
VUHAHULA, E;NIKAI, H;TANIMOTO, K
本文对12例上皮角化突出的颌骨囊肿的临床病理、免疫组织化学和放射学特征进行了研究，并与典型的牙源性角化囊肿和含牙囊肿进行了比较。在生物学行为和组织病理学表现方面，它们与牙源性角化囊肿有显著不同。尽管上皮衬里细胞角蛋白、EMA、CEA和总蛋白的免疫组织化学染色没有揭示这些病变的组织起源，但这些标记物的染色模式与牙源性角化囊肿和非角化含牙囊肿显著不同。放射学上，9例表现为含牙囊肿；2例，1例皮脂腺分化，表现为非含牙单眼囊肿；1例特殊，组织学上可见多个表皮囊肿，真皮附件突出。提示颌骨正角化囊肿可能属于不同于牙源性角化囊肿的临床病理实体，多数为正角化的含牙囊肿。也要考虑罕见的中央皮样或表皮样囊肿存在的可能性。
The clinico-pathologic, immunohistochemical and radiological features of 12 jaw cysts with a prominent orthokeratinized epithelial lining were studied and compared with those of typical odontogenic keratocysts and dentigerous cysts. They differed significantly from odontogenic keratocysts in terms of biologic behavior and histopathologic findings. Although immunohistochemical staining of the epithelial linings for cytokeratins, EMA, CEA and involucrin has not shed any light on the histogenesis of these lesions, staining patterns for these markers were significantly different from those of odontogenic keratocysts and non-keratinized dentigerous cysts. Radiologically, nine cases appeared as dentigerous cysts; two cases, one with sebaceous differentiation, as non-dentigerous unilocular cysts, and the remaining one was exceptional as it showed multiple epidermal cysts with prominent dermal appendages histologically. It is suggested that most of the orthokeratinized jaw cysts may belong to clinico-pathological entities different from odontogenic keratocysts with the majority representing dentigerous cysts with orthokeratinization. The possibility of the existence of rare central dermoid or epidermoid cysts is also to be considered.