Phosphine catalyzed α-arylation of enones and enals using hypervalent bismuth reagents:: Regiospecific enolate arylation via nucleophilic catalysis
Phosphine catalyzed α-arylation of enones and enals using hypervalent bismuth reagents:: Regiospecific enolate arylation via nucleophilic catalysis
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DOI：
10.1021/ja048987i
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发表时间：
2004-05-05
影响因子：
15
通讯作者：
Krische, MJ
中科院分区：
文献类型：
--
作者：
Koech, PK;Krische, MJ
在二氯化三芳基铋 (V) 存在下，将烯酮和烯醛暴露于 20 mol% 三丁基膦，导致区域特异性芳基转移至烯酮或烯醛亲核试剂的 α 位。这些结果代表了在亲核催化条件下烯醇化芳基化的第一个例子。
Exposure of enones and enals to 20 mol % tributylphosphine in the presence of triarylbismuth(V) dichlorides results in regiospecific aryl transfer to the α-position of the enone or enal pronucleophile. These results represent the first examples of enolate arylation under the conditions of nucleophilic catalysis.