Analysis of increasing and decreasing isometric finger force generation and the possible role of the corticospinal system in this process.
Analysis of increasing and decreasing isometric finger force generation and the possible role of the corticospinal system in this process.
复制标题
分析增加和减少等长手指力的产生以及皮质脊髓系统在此过程中可能发挥的作用。
DOI：
10.1123/mcj.17.3.221
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发表时间：
2013
期刊：
影响因子：
1.1
通讯作者：
Li,Sheng
中科院分区：
文献类型：
--
作者：
Li,Sheng
本研究探讨了皮质脊髓系统在力产生和力松弛过程中的可能作用。九名年轻健康的受试者被指示产生一个总的力量与四个手指在一只手后，预先设定的力产生和放松斜坡模板密切。皮质脊髓（CS）预测的兴奋性进行了评估单脉冲和成对脉冲TMS。由手指力引入的误差在力产生期间由其他手指力部分补偿，但在力松弛期间被放大。CS的兴奋性是更大的力产生过程中比维持或放松。皮层内抑制或易化没有差异，非标准化的手指伸肌肌电图反应保持不变。研究结果表明，力量放松不仅仅是从激活中退出，多指互动可能在初级运动皮层之外受到控制。
This study investigated the possible role of the corticospinal system during force generation and force relaxation. Nine young and healthy subjects were instructed to produce a total force with four fingers within a hand following a preset force generation and relaxation ramp template closely. Excitability of corticospinal (CS) projections was assessed by single- and paired-pulse TMS. Errors introduced by a finger force were partially compensated by other finger forces during force generation, but were amplified during force relaxation. The CS excitability was greater during force generation than maintenance or relaxation. No difference in intracortical inhibition or facilitation was found. Nonnormalized finger extensor EMG responses remained unchanged. The findings suggest that force relaxation is not just a withdrawal from activation, and multifinger interactions are likely controlled beyond the primary motor cortex.