The impact of a Facebook campaign among mothers on HPV vaccine uptake among their daughters: A randomized field study
The impact of a Facebook campaign among mothers on HPV vaccine uptake among their daughters: A randomized field study
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脸书宣传活动对母亲为女儿接种人乳头瘤病毒（HPV）疫苗意愿的影响：一项随机实地研究
DOI：
10.1016/j.ygyno.2020.10.037
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发表时间：
2021-01-01
影响因子：
4.7
通讯作者：
Lewis, Nehama
中科院分区：
文献类型：
--
作者：
Chodick, Gabriel;Teper, Gally Rosenfeld;Lewis, Nehama
目标。社交网络的普及为加强预防医学项目的影响提供了一个难以置信的机会。我们的目的是评估在母亲中开展有针对性的Facebook活动是否可以增加其8年级女儿对人乳头瘤病毒（HPV）免疫接种的吸收。这项实地研究是在以色列一个国家授权的卫生组织的成员中进行的。其中包括在2018-19学年为14岁女儿的母亲的21,592名成员。共有17271人（80%）被随机分配到运动组，其余的（n= 4321）被选为参照组。Facebook的广告解决了有关HPV相关疾病和HPV疫苗的问题和担忧。主要结果测量是脸谱网对研究参与者的八年级女儿接触运动和HPV免疫的度量。在2018年8月至2018年10月期间，Facebook广告被展示了180万次（覆盖率为88%）。分配到运动组的妇女的女儿中HPV疫苗的接种率（55.3%）与对照组的55.0%相似（p = 0.749）。当按SES水平分层时，观察到研究组之间的唯一显著差异。在社会经济地位最低的四分位数中，Facebook活动显著（p = 0.02）降低了疫苗接种率（35% vs. 39.0%），相对危险度为0.90 (95%CI: 0.82-0.98)，而在社会经济地位最低的四分位数中，Facebook活动将疫苗接种率从52.6%提高到55.8%，相对危险度为1.06 （95%CI,1.00-1.12）。在较高SES水平的母亲中，暴露母亲和未暴露母亲的女儿免疫接种率相似。Facebook活动可能会增加中低经济地位母亲的女儿对HPV疫苗的接种率，但可能会减少低经济地位群体的疫苗接种率。(C) 2020作者。Elsevier Inc.出版。
Objective. The popularity of social networks provide an incredible opportunity to enhance the impact of preventive medicine programs. We aimed to assess whether a targeted Facebook campaign among mothers may increase the uptake of human Papilloma virus (HPV) immunization among their 8th-grade daughters.Methods. This field study was conducted among the members of a state-mandated health organization in Israel. Included were all 21,592 members who were mothers to 14 year-old daughters in the 2018-19 school-year. A total of 17,271 (80%) were randomly allocated to the campaign arm and the rest (n=4,321) were selected as a reference group. The Facebook ads addressed issues and concerns regarding HPV-related diseases and HPV vaccine. Main outcome measures were Facebook metrics on exposure to campaign and HPV immunization among eighth grade daughters of the study participants.Results. Between 8/2018-10/2018, Facebook ads were shown 1.8-million times (a reach of 88%). The uptake of HPV vaccine among daughters of women allocated to the campaign arm (55.3%) was similar (p = 0.749) to 55.0% in the control group. The only significant differences between study groups were observed when stratifying by SES level. In the lowest SES quartile, Facebook campaign significantly (p = .02) reduced vaccine uptake (35% vs. 39.0%), with a relative risk of 0.90 (95%CI: 0.82-0.98), while in the second SE quartile, Facebook campaign increased vaccine uptake from 52.6% to 55.8%, with a RR of 1.06 (95%CI,1.00-1.12). Among mothers in higher SES levels, daughters of exposed and unexposed mothers had similar immunization rates.Conclusions. Facebook campaign may increase the uptake of HPV vaccine among daughters to mothers of medium-to-low SES level, but it may reduce vaccination among lower SES groups. (C) 2020 The Authors. Published by Elsevier Inc.