Interaction of membrane systems in blood platelets.

Interaction of membrane systems in blood platelets.
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血小板膜系统的相互作用。

DOI:
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发表时间:
1972
影响因子:
6
通讯作者:
J. White
J. White
中科院分区:
医学2区
文献类型:
--
作者:
J. White

文献摘要

被引文献

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血小板中存在两组独立的膜封闭通道,即开放小管系统(OCS)和致密小管系统(DNT),这一点已被认识多年。本研究采用超微结构观察正常血小板,细胞从一个孩子的灰色血小板综合征和细胞化学定位的过氧化物酶在血小板定义的起源,并指出一个专门的膜复合物形成的通道的相互作用,从OCS和血小板膜。血小板膜复合物的相似之处,在肌肉中的膜系统的组织指出,和他们的潜在功能作为肌浆网的血小板进行了讨论。
The existence of two separate groups of membrane-enclosed channels in platelets, the open canalicular system (OCS) and the dense tubular system (DTS), has been recognized for several years. The present study has employed ultrastructural observations on normal platelets, cells from a child with the gray platelet syndrome and cytochemical localization of peroxidase in platelets to define the origin of the DTS and point out a specialized membrane complex in platelets formed by interaction of channels from the OCS and DTS. The similarities of membrane complexes in platelets to the organization of membrane systems in muscle is pointed out, and their potential function as the sarcoplasmic reticulum of platelets is discussed.