The synthesis of DNA by membrane-DNA complexes from E. coli B-r and Bs-1 after exposure to fast electrons and neutrons: the measurement of oxygen-enhancement ratios and RBE values.
The synthesis of DNA by membrane-DNA complexes from E. coli B-r and Bs-1 after exposure to fast electrons and neutrons: the measurement of oxygen-enhancement ratios and RBE values.
复制标题
暴露于快电子和中子后，大肠杆菌 B-r 和 Bs-1 的膜-DNA 复合物合成 DNA：氧增强比和 RBE 值的测量。
DOI：
10.1080/09553007214551231
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发表时间：
1972
期刊：
影响因子：
--
通讯作者：
J. Collins
中科院分区：
文献类型：
--
作者：
W. Cramp;D. Watkins;J. Collins
摘要
大肠杆菌B/r和Bs - 1经辐照后，其DNA - 膜复合物的DNA合成活性降低。在有氧条件下，用快电子辐照时，这两种菌株的该活性降低程度比在无氧条件下高7到8倍。对于中子，大肠杆菌B/r和大肠杆菌Bs - 1的氧增强比分别为4.0和5.2。
耐辐射的大肠杆菌B/r和辐射敏感的大肠杆菌Bs - 1的复合物的DNA合成能力受电子辐照的抑制程度相同，但用快中子辐照时，大肠杆菌B/r的DNA - 膜复合物的合成活性比大肠杆菌Bs - 1受到的抑制更明显。
SummaryIrradiation of E. coli B/r and Bs−1 depressed the DNA synthetic activity of the DNA-membrane complexes from these bacteria. The depression of this activity in both strains in the presence of oxygen was seven to eight times greater than under anoxic conditions when irradiation was with fast electrons. The oxygen-enhancement ratios for neutrons were 4·0 and 5·2 for E. coli B/r and E. coli Bs−1, respectively.The DNA-synthesizing abilities of complexes from the radiation-resistant E. coli B/r and the radisation-sensitive E. coli Bs−1 were equally inhibited by electron irradiation, but with fast neutrons the synthetic activity of the DNA-membrane complex from E. coli B/r was more inhibited than that from E. coli Bs−1.