Diffusion tensor anisotropy in adolescents and adults
Diffusion tensor anisotropy in adolescents and adults
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DOI：
10.1159/000104277
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发表时间：
2007-01-01
影响因子：
3.2
通讯作者：
Hof, Patrick R.
中科院分区：
文献类型：
--
作者：
Schneiderman, Jason S.;Buchsbaum, Monte S.;Hof, Patrick R.
我们获得了33名年龄在22-64岁的正常成年人和15名年龄在14-21岁的青少年的扩散张量图像。我们评估了内囊、胼胝体、前丘脑放射、额前束、额枕束、颞叶白色物质、扣带回束、额下纵束、额上级纵束和视放射中立体定位感兴趣区域的相对各向异性。除视放射、胼胝体和额下纵束外，其他结构的各向异性在青少年和成人之间均存在差异。各向异性随年龄增加的区域包括内囊前肢、额上级纵束的上级水平和颞部白色物质的下部。各向异性随年龄增长而降低的区域包括内囊后肢、丘脑前放射、额枕束、额前束前部、额上级纵束下部、扣带束和颞轴上级部。性别差异在大多数领域，但最显着的扣带束和内囊。这些结果表明，在青春期和成年期之间，白色物质的发育是持续的。版权所有（c）2007 S. Karger AG，巴塞尔。
We acquired diffusion tensor images on 33 normal adults aged 22-64 and 15 adolescents aged 14-21. We assessed relative anisotropy in stereotaxically located regions of interest in the internal capsule, corpus callosum, anterior thalamic radiations, frontal anterior fasciculus, fronto-occipital fasciculus, temporal lobe white matter, cingulum bundle, frontal inferior longitudinal fasciculus, frontal superior longitudinal fasciculus, and optic radiations. All of these structures except the optic radiations, corpus callosum, and frontal inferior longitudinal fasciculus exhibited differences in anisotropy between adolescents and adults. Areas with anisotropy increasing with age included the anterior limb of the internal capsule, superior levels of the frontal superior longitudinal fasciculus and the inferior portion of the temporal white matter. Areas with anisotropy decreasing with age included the posterior limb of the internal capsule, anterior thalamic radiations, fronto-occipital fasciculus, anterior portion of the frontal anterior fasciculus, inferior portion of the frontal superior longitudinal fasciculus, cingulum bundle and superior portion of the temporal axis. Sex differences were found in the majority of areas but were most marked in the cingulum bundle and internal capsule. These results suggest continuing white matter development between adolescence and adulthood. Copyright (c) 2007 S. Karger AG, Basel.