Occurrence and distribution of selected pharmaceuticals and personal care products in aquatic environments: a comparative study of regions in China with different urbanization levels
Occurrence and distribution of selected pharmaceuticals and personal care products in aquatic environments: a comparative study of regions in China with different urbanization levels
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DOI：
10.1007/s11356-012-0750-2
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发表时间：
2012-07-01
影响因子：
5.8
通讯作者：
Zhu, Saichang
中科院分区：
文献类型：
--
作者：
Chen, Hong;Li, Xiaojuan;Zhu, Saichang
分析比较了杭州市市区和临南县不同水样中13种靶药的分布。在钱塘江5家医院、2家污水处理厂和钱塘江进行采样。固相萃取法对样品进行浓缩，UPLC-MS/MS法测定PPCP浓度。甲氧苄啶、二水合红霉素A、诺氟沙星、氧氟沙星、双氯芬酸钠和阿替洛尔是医院污水中检出最多的药物。医院污水中大部分药物浓度高于污水处理厂污水。虽然两种污水处理厂均采用厌氧-好氧-缺氧处理工艺，但对甲氧苄啶和双氯芬酸钠等药物的去除率完全不同。钱塘江中还检出了二水红霉素A、氧氟沙星、青霉素- g、头孢氨苄、头孢唑林、布洛芬和双氯芬酸钠。这些结果表明，医院是药物的集中来源，而污水处理厂不是药物进入这两个地区水生环境的唯一途径。
We analyzed and compared the distributions of 13 target pharmaceuticals in different water samples from the Hangzhou metropolitan area and Linan County, Southeast China.Sampling was conducted in five hospitals, two wastewater treatment plants (WWTPs), and Qiantang River. Samples were concentrated by solid-phase extraction and PPCP concentrations were determined by UPLC-MS/MS.Trimethoprim, erythromycin A dihydrate, norfloxacin, ofloxacin, diclofenac sodium, and atenolol were the most frequently detected pharmaceuticals in hospital effluents. Most of the pharmaceutical concentrations in hospital effluents were higher than those in the WWTP influents. Although both WWTPs adopt the anaerobic-aerobic-anoxic treatment process, the removal rates for pharmaceuticals, such as trimethoprim and diclofenac sodium, were completely different. Meanwhile, erythromycin A dihydrate, ofloxacin, penicillin-G, cephalexin, cefazolin, ibuprofen, and diclofenac sodium were detected in Qiantang River.These results indicate that hospitals are more concentrated sources of pharmaceuticals than WWTPs, and the WWTPs are not the only route of entry of pharmaceuticals into aquatic environments in these two regions.