INTEGRATING SYSTEMATIC CUE EXPOSURE WITH STANDARD TREATMENT IN RECOVERING DRUG DEPENDENT PATIENTS
INTEGRATING SYSTEMATIC CUE EXPOSURE WITH STANDARD TREATMENT IN RECOVERING DRUG DEPENDENT PATIENTS
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DOI：
10.1016/0306-4603(90)90045-y
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发表时间：
1990-01-01
影响因子：
4.4
通讯作者：
EHRMAN, R
中科院分区：
文献类型：
--
作者：
OBRIEN, CP;CHILDRESS, AR;EHRMAN, R
反复给药很容易在动物和人类实验研究中产生经典的条件性反应。大多数申请药物依赖治疗的患者在接触到与药物相关的刺激时，既表现出自主反应，也表现出主观反应。这些反应被认为是在活跃的药物使用期间形成的，在药物依赖的传统治疗后持续存在，并可能构成易复发的几个因素之一。提供了一种新的治疗方法的初步数据，该方法旨在测试全身暴露于与药物有关的线索是否可以减少或消除药物条件反应，以及这种消退是否改善了治疗的整体结果。
Repeated drug administration readily produces classically conditioned reponses in animal and human experimental studies. The majority of patients applying for treatment of drug dependence show both autonomic and subjective responses when exposed to drug-related stimuli. These responses are presumed to have been conditioned during a period of active drug use, persist after traditional treatment for drug dependence, and may constitute one of several factors which predispose to relapse. Preliminary data are presented from a novel treatment approach which is designed to test whether drug-conditioned responses can be reduced or extinguished by systemic exposure to drug-related cues and whether such extinction improves the overall results of treatment.