Validation of Rapid Neurodevelopmental Assessment for 2-to 5-Year-Old Children in Bangladesh
Validation of Rapid Neurodevelopmental Assessment for 2-to 5-Year-Old Children in Bangladesh
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DOI：
10.1542/peds.2011-2421
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发表时间：
2013-02-01
期刊：
影响因子：
8
通讯作者：
Darmstadt, Gary L.
中科院分区：
文献类型：
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作者：
Khan, Naila Z.;Muslima, Humaira;Darmstadt, Gary L.
目的：快速神经发育评估（RNDA）是一种旨在检测多个神经发育领域的功能状态和神经发育障碍（NDI）的工具。在达卡通过挨家挨户抽样招募了77名儿童，并由6名测试者中的1名进行RNDA管理，（4名发展治疗师，2名特殊教育教师），同时进行适应行为测试（AB;独立行为评估量表）和智商（IQ）测试（Bayley婴儿发展量表II、斯坦福大学Binet智力量表、Wechsler学龄前和小学智力量表）。在独立行为评估量表中，运动（P = .0001）、社会化（P =.001）、沟通（P =.001）和全量表（P =.001）评分中，NDI>= 1（“任何NDI”）的儿童与无NDI的儿童的AB平均百分位数评分存在显著差异。有“任何NDI”者与无“任何NDI”者在智商得分上有显著差异。“重大困难”（定义为AB z评分< -2 SD和/或IQ < 70）和“轻度困难”（AB z评分<-1 SD和/或IQ < 70）的敏感性和特异性
OBJECTIVE: Validate a tool to determine neurodevelopmental impairments (NDIs) in >2- to 5-year-old children in a country with limited child development expertise.METHODS: Rapid Neurodevelopmental Assessment (RNDA) is a tool designed to detect functional status and NDIs across multiple neurodevelopmental domains. Validity was determined in 77 children enrolled by door-to-door sampling in Dhaka and who were administered the RNDA by 1 of 6 testers (4 developmental therapists, 2 special education teachers) and simultaneously administered a test of adaptive behavior (AB; Independent Behavior Assessment Scale) and intelligence quotient (IQ) tests (Bayley Scales of Infant Development II, Stanford Binet Intelligence Scale, Wechsler Preschool and Primary Scales of Intelligence) by psychologists.RESULTS: Interrater reliability ranged from good to excellent. There were significant differences in AB in mean percentile scores on the Independent Behavior Assessment Scale for motor (P = .0001), socialization (P = .001), communication (P = .001), and full-scale (P = .001) scores in children with >= 1 NDI ("any NDI") versus no NDI. Significant differences in those with versus those without "any NDI" were found on IQ scores. Sensitivity and specificity for "significant difficulties" (defined as AB z-scores < -2 SDs and/or IQ < 70) and "mild difficulties included" (AB z-scores < -1SD and/or IQ