Identification of four additional myoinhibitory peptides (MIPs) from the ventral nerve cord of Manduca sexta
Identification of four additional myoinhibitory peptides (MIPs) from the ventral nerve cord of Manduca sexta
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DOI：
10.1002/arch.1064
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发表时间：
2001-11-01
影响因子：
2.2
通讯作者：
Raina, AK
中科院分区：
文献类型：
--
作者：
Blackburn, MB;Jaffe, H;Raina, AK
从成虫腹侧神经索中分离和鉴定了4个新的肌抑制肽。这两个新多肽的序列分别为APEKWAAFHGSWAME(MAS-MIP III)、GWNDMSSAWAME(MAS-MIP IV)、GWQDMSSAWAME(MAS-MIP V)和AWSALHGAWAME(MAS-MIP VI)。MAS-MIPs III-VI在体外可抑制成体后肠(回肠)的自发蠕动。2001年出版，Wiley-Liss，Inc.
Four new myoinhibitory peptides were isolated and identified from the ventral nerve cord of adult Manduca sexta. The new peptides are related to two previously identified myoinhibitory peptides also isolated from adult M. sexta, Alas-MIP I and Mas-MIP II. The sequences of the new peptides are APEKWAAFHGSWamide (Mas-MIP III), GWNDMSSAWamide (Mas-MIP IV), GWQDMSSAWamide (Mas-MIP V), and AWSALHGAWamide (Mas-MIP VI). Mas-MIPs III-VI were found to inhibit spontaneous peristalsis of the adult M. sexta anterior hindgut (ileum) in vitro. Published 2001 Wiley-Liss, Inc.