Regeneration Genetics.

Regeneration Genetics.
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DOI:
10.1146/annurev-genet-120116-024554
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发表时间:
2017-11-27
影响因子:
11.1
通讯作者:
Poss KD
Poss KD
中科院分区:
生物学1区
文献类型:
--
作者:
Chen CH;Poss KD

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Understanding how and why animals regenerate complex tissues has potential to transform regenerative medicine. Here we present an overview of genetic approaches that have recently been applied to dissect mechanisms of regeneration. We describe new advances that relate to central objectives of regeneration biolsts researching different tissues and species. These objectives include defining the cellular sources and key cell behaviors in regenerating tissue; elucidating molecular triggers and brakes for regeneration; and defining the earliest events that control the presence of these molecular factors.
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