Transgenic animals resistant to infectious diseases.
Transgenic animals resistant to infectious diseases.
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DOI：
10.20506/rst.35.1.2422
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发表时间：
2016-04
期刊：
影响因子：
--
通讯作者：
L. Tiley
中科院分区：
文献类型：
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作者：
L. Tiley
为测试生产抗传染病牲畜的方法而开发的转基因动物的名单继续增加。尽管自世界动物卫生组织上次审查以来，生产转基因动物的基本技术在十年内没有太大变化，但最近的一项基本技术进步将彻底改变基因组工程。技术上简单而有效的位点特异性基因靶向的出现对转基因牲畜物种具有深远的影响。
The list of transgenic animals developed to test ways of producing livestock resistant to infectious disease continues to grow. Although the basic techniques for generating transgenic animals have not changed very much in the ten years since they were last reviewed for the World Organisation for Animal Health, one recent fundamental technological advance stands to revolutionise genome engineering. The advent of technically simple and efficient site-specific gene targeting has profound implications for genetically modifying livestock species.