Prediction of glucose and insulin responses of normal subjects after consuming mixed meals varying in energy, protein, fat, carbohydrate and glycemic index.
Prediction of glucose and insulin responses of normal subjects after consuming mixed meals varying in energy, protein, fat, carbohydrate and glycemic index.
复制标题
预测正常受试者食用不同能量、蛋白质、脂肪、碳水化合物和血糖指数的混合膳食后的葡萄糖和胰岛素反应。
DOI：
10.1093/jn/126.11.2807
复制
发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Claudia Bolognesi
中科院分区：
文献类型：
--
作者：
T. Wolever;Claudia Bolognesi
为了了解碳水化合物的摄入量和来源是否决定了混合餐的餐后血糖和胰岛素反应，8名非糖尿病受试者服用了5种不同的混合餐，其中含有可变能量（1650-2550 kJ）、脂肪（8-24 g）、蛋白质（12-25 g）、碳水化合物（38-104 g）和血糖指数（43-99）。五餐的葡萄糖和胰岛素反应增量在2.3倍范围内变化。单独的碳水化合物的量与平均葡萄糖和胰岛素反应没有显著相关。然而，使用先前推导的方程，碳水化合物的量和血糖指数解释了观察到的平均葡萄糖和胰岛素反应的变异性的约90%（P = 0.01）。我们的结论是，无论是数量和来源的碳水化合物确定的葡萄糖和胰岛素的反应瘦，年轻，非糖尿病受试者后，不同的混合餐与可变的血糖指数。蛋白质和脂肪摄入量的变化，在这里测试的范围内，似乎对餐后血糖和胰岛素的影响可以忽略不计。
To see if both the amount and source of carbohydrate consumed determined postprandial glucose and insulin responses of mixed meals, eight nondiabetic subjects took five different mixed meals containing variable energy (1650-2550 kJ), fat (8-24 g), protein (12-25 g) carbohydrate (38-104 g) and glycemic index (43-99). Incremental glucose and insulin responses for the five meals varied over a 2.3-fold range. Amount of carbohydrate alone was not significantly related to the mean glucose and insulin responses. However, using previously derived equations, amount of carbohydrate and glycemic index explained approximately 90% of the variability of the observed mean glucose and insulin responses (P = 0.01). We conclude that both amount and source of carbohydrate determine the glucose and insulin responses of lean, young, nondiabetic subjects after different mixed meals with variable glycemic index. Variation in protein and fat intake, over the range tested here, appears to have a negligible effect on postprandial glucose and insulin.