Developmental changes in brain TRH and in plasma and pituitary TSH and prolactin levels in the rat.
Developmental changes in brain TRH and in plasma and pituitary TSH and prolactin levels in the rat.
复制标题
大鼠大脑 TRH 以及血浆和垂体 TSH 和催乳素水平的发育变化。
DOI：
10.1159/000241266
复制
发表时间：
1980
期刊：
影响因子：
--
通讯作者：
J. C. Porter
中科院分区：
文献类型：
--
作者：
C. Oliver;R. Eskay;J. C. Porter
用放射免疫法测定了不同年龄大鼠(10-22天胎鼠和1-60天龄大鼠)下丘脑和脑其他部分的TRH，以及脑垂体腺和血浆中的TSH和催乳素。TRH在妊娠第16天首次被检测到，在生命的前3周，其峰值出现在下丘脑和大脑的其余部分。本文还讨论了血浆和脑下垂体中TSH和催乳素的进化模式与脑和下丘脑中TRH水平的关系。
TRH in the hypothalamus and the rest of the brain, as well as TSH and prolactin in the pituitary gland and the plasma have been determined by radioimmunoassay in rats varying in age (10- to 22-day-old fetuses and 1- to 60-day-old rats). TRH is first detected on the 16th day of gestation and its maximum increase occurs during the first 3 weeks of life both in the hypothalamus and the rest of the brain. The evolution patters of TSH and prolactin in the plasma and the pituitary gland are discussed in relation to TRH levels in the brain and in the hypothalamus.