5-HT induced accumulation of 3',5'-AMP and the phosphorylation of paramyosin in the ABRM of Mytilus edulis.
5-HT induced accumulation of 3',5'-AMP and the phosphorylation of paramyosin in the ABRM of Mytilus edulis.
复制标题
5-HT 诱导贻贝 ABRM 中 3,5-AMP 的积累和副肌球蛋白的磷酸化。
作者：
Achazi Rk
在紫贻贝（Mytilus edulis）中，5-Ht诱导的肌肉松弛之前是3 '，5'-AMP含量的增加。在体外，收缩器的两种蛋白质被3 '，5'-AMP依赖性蛋白激酶磷酸化。295000道尔顿的蛋白不能被鉴定，另一个是副肌球蛋白。磷酸化副肌球蛋白在低和高Ca++浓度下抑制软体动物平滑肌肌动球蛋白ATP酶。
In Mytilus edulis 5-Ht induced relaxation of a muscle in catch is preceded by an increase in 3',5'-AMP content. In vitro two proteins of the contractile apparatus are phosphorylated by 3',5'-AMP dependent protein kinases. The 295000 dalton protein cannot be identified, the other one is paramyosin. Phosphorylated paramyosin inhibits actomyosin ATPase of smooth mollusc muscles at low and high Ca++ concentrations.