Factors associated with incidence and persistence of symptoms of disturbed sleep in an elderly cohort: The cardiovascular health study
Factors associated with incidence and persistence of symptoms of disturbed sleep in an elderly cohort: The cardiovascular health study
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DOI：
10.1097/00000441-200504000-00001
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发表时间：
2005-04-01
影响因子：
3.1
通讯作者：
Newman, A
中科院分区：
文献类型：
--
作者：
Quan, SF;Katz, R;Newman, A
背景：有关影响老年人睡眠症状发生率和持续时间的因素的数据有限。本研究的目的是确定心血管健康研究 (CHS) 中以下睡眠症状的发生率和未缓解率：入睡困难 (TFA)、频繁醒来 (FA) 和白天过度嗜睡 (EDS)，心血管健康研究 (CHS) 是一项针对老年人心血管疾病的前瞻性多中心研究。还评估了影响这些比率的因素。方法：对 4467 名 CHS 参与者进行了调查，了解他们在基线检查和 1 至 4 年后的随访检查中是否存在 TFA、FA 和 EDS 以及其他健康问题。结果：年发生率和无缓解率如下：TFA（2.8% 和 15.4%）、FA（12.3% 和 22.7%）和 EDS（4.4% 和 13.4%）。女性更容易发生偶发性和持续性 TFA。抑郁是预测所有三种睡眠症状发生率的主要因素。然而，其他健康状况，包括呼吸道症状和心血管疾病，以及日常生活活动的限制也很重要。抑郁也是与这些睡眠症状持续存在相关的最重要因素。其他健康状况在确定未缓解方面的作用要有限得多。结论：老年人睡眠障碍的发生与抑郁、健康状况和身体机能有关。然而，睡眠障碍的持续存在最好是通过抑郁症的存在来预测。
Background: There are limited data pertaining to the factors influencing the incidence and persistence of sleep symptoms in the elderly. The purpose of this study was to determine the incidence and nonremission rates of the following sleep symptoms: trouble falling asleep (TFA), frequent awakenings (FA), and excessive daytime sleepiness (EDS) in the Cardiovascular Health Study (CHS), a prospective multicenter study of cardiovascular disease in a large cohort of elderly adults. Factors influencing these rates were assessed as well. Methods: 4467 participants in CHS were surveyed for the presence of TFA, FA, and EDS as well as other health problems at their baseline examination and at a follow-up examination I to 4 years later. Results: Annualized incidence and nonremission rates were the following: TFA (2.8% and 15.4%), FA (12.3% and 22.7%), and EDS (4.4% and 13.4%). Women were more likely to have incident and persistent TFA. Depression was the primary factor predicting the incidence of all three sleep symptoms. However, other health conditions, including respiratory symptoms and cardiovascular disease, and limitation in activities of daily living were important as well. Depression also was the most important factor associated with persistence of these sleep symptoms. The role of other health conditions in determining non-remission was much more limited. Conclusions: Incidence of sleep disturbances in the elderly is related to depression, health conditions, and physical functioning. However, persistence of sleep disturbances is best predicted by the presence of depression.