Additive variation maintained under stabilizing selection: a two-locus model of pleiotropy for two quantitative characters.
Additive variation maintained under stabilizing selection: a two-locus model of pleiotropy for two quantitative characters.
复制标题
在稳定选择下维持加性变异：两个数量性状的多效性的双基因座模型。
DOI：
10.1093/genetics/112.3.717
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发表时间：
1986
期刊：
影响因子：
3.3
通讯作者：
Gimelfarb,A
中科院分区：
文献类型：
--
作者：
Gimelfarb,A
提出了由两个双等位基因控制两个加性数量性状的模型。其中一个座位对两个性状有相似的效应，而第二个座位对两个性状有拮抗作用。两个角色都经历了直接稳定的选择。该模型产生稳定的多态状态，两个性状都保持遗传变异。处于平衡状态的性状之间的遗传相关为零，尽管控制它们的基因座具有多效性。
A model with two diallelic loci controlling two additive quantitative characters is suggested. One of the loci has a similar effect on both characters, whereas the second locus has an antagonistic effect on the two characters. Both characters experience direct stabilizing selection. The model yields a stable polymorphic state, with both characters maintaining genetic variation. The genetic correlation between the characters at the equilibrium is zero, in spite of the pleiotropic effects of the loci controlling them.