Noncirrhotic Extrahepatic and Intrahepatic Portal Hypertension
Noncirrhotic Extrahepatic and Intrahepatic Portal Hypertension
复制标题
非肝硬化肝外和肝内门脉高压
DOI：
10.1055/s-2008-1040708
复制
发表时间：
1982
影响因子：
4.2
通讯作者：
S. Sherlock
中科院分区：
文献类型：
--
作者：
S. Sherlock
在没有肝硬化的情况下，多种情况可能导致门脉高压的发生。实际上在所有情况下，门静脉、血窦或肝静脉水平的血流阻力增加是导致门静脉压力升高的主要因素，尽管在某些情况下血流增加可能是一个促成因素。静脉曲张出血是这些疾病的主要并发症，但由于肝细胞功能更好，其耐受性比肝硬化更好。一般来说，治疗应该是保守的，并针对任何可以识别的潜在病理。
A variety of conditions may lead to the development of portal hypertension in the absence of cirrhosis. In virtually all cases, increased resistance to flow at the level of the portal vein, sinusoids, or hepatic vein is the major contributing factor to the elevated portal pressure, although increased flow may be a contributor in certain instances. Variceal hemorrhage is the major complication of these disorders, but is better tolerated than in cirrhosis because of better hepatocellular function. Therapy should in general be conservative and directed toward any underlying pathology, where such can be identified.