Sensitivity and specificity of anthropometrics for the prediction of diabetes in a biracial cohort
Sensitivity and specificity of anthropometrics for the prediction of diabetes in a biracial cohort
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DOI：
10.1038/oby.2001.94
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发表时间：
2001-11-01
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影响因子：
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通讯作者：
Tyroler, HA
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文献类型：
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作者：
Stevens, J;Couper, D;Tyroler, HA
目的：评估体重指数、腰围、腰臀比以及这些变量的组合区分成年后患糖尿病的能力。 研究方法和程序：数据来自社区动脉粥样硬化风险队列成员的 45 至 64 岁男性和女性。分析样本由 12,814 名非裔美国人和白人参与者组成，他们在基线时没有患糖尿病。体重指数、腰围、腰臀比和糖尿病发病率（定义为禁食至少 8 小时后一项血糖测量值大于或等于 126 mg/dL，一项非空腹血糖测量值大于或等于 200 mg/dL，以及糖尿病的自我报告或服用糖尿病药物的报告）。结果：在 9 年的随访中，发现了 1515 例新的糖尿病病例。单次测量的接收者操作特征曲线下面积范围为 0.66 至 0.73。曲线平滑，没有阈值迹象。在所有组中，腰围往往具有最高的接收者操作特征统计数据，但差异很小。讨论：测试的三个人体测量指数在预测糖尿病的能力方面大致相当。种族和性别群体之间的敏感性和特异性不同。
Objective: To evaluate the ability of body mass index, waist circumference, waist-to-hip ratio, and combinations of these variables to discriminate individuals who will develop diabetes in adulthood.Research Methods and Procedures: Data were from 45- to 64-year-old men and women who were members of the Atherosclerosis Risk in Communities cohort. The analysis sample consisted of 12,814 African American and white participants who were free of diabetes at baseline. Body mass index, waist circumference, waist-to-hip ratio, and diabetes incidence (defined as one glucose measure greater than or equal to 126 mg/dL after fasting for at least 8 hours, one nonfasting glucose measure greater than or equal to 200 mg/dL, and self-report of diabetes or report of taking medication for diabetes).Results: 1515 new cases of diabetes were identified over the 9-year follow-up. Areas under receiver operating characteristic curves ranged from 0.66 to 0.73 for single measures. The curves were smooth, with no indication of a threshold. Waist tended to have the highest receiver operating characteristic statistic in all groups, but differences were small.Discussion: The three anthropometric indices tested were approximately equivalent in their ability to predict diabetes. Sensitivity and specificities differed among ethnic and gender groups.