Particle Accumulation by AC Electroosmosis in Microfluidic Device with Co-Planar Electrodes
Particle Accumulation by AC Electroosmosis in Microfluidic Device with Co-Planar Electrodes
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DOI：
10.1299/jtst.7.475
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发表时间：
2012-08
影响因子：
1.2
通讯作者：
A. Ishida;Hikaru Toki;M. Motosuke;S. Honami
中科院分区：
文献类型：
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作者：
A. Ishida;Hikaru Toki;M. Motosuke;S. Honami
本文报道了交流电渗透(ACEs)在共面电极微流控装置中的颗粒聚集。研究了颗粒在单间隙和双间隙电极器件中的积累过程。分别用微米级粒子跟踪测速仪和荧光强度分析法测量了ACEs的流场和流动诱导的颗粒聚集过程。溶液中的颗粒从靠近入口处缝隙的电极边缘逐渐集中，并汇聚到下游的某个位置。讨论了ACeO对颗粒输运和最终积累的贡献，并评价了实验参数对积累位置的依赖关系。颗粒的浓度行为可分为两种类型，一种是在两种缝隙模式下具有相似的聚集特性，另一种是颗粒集中在通道中心跨度的情况。因此，本研究的结果表明，在单间隙装置的基础上，在具有更复杂的电极几何的装置中估计颗粒浓度是可能的。ACEP粒子聚焦方法有助于提高微流控系统的检测灵敏度。
This paper reports a particle accumulation driven by alternating-current electroosmosis (ACEO) in a microfluidic device with co-planar electrode. Accumulation processes of particles in singleand double-gap electrode device were investigated. The flow field of ACEO and flow-induced particle accumulation process were measured by the micron-resolution particle tracking velocimetry and fluorescent intensity analysis, respectively. Particles in a solution are concentrated gradually from an electrode edge close to gap at the entrance and converged into a certain location downstream. Contribution of ACEO to particle transportation and eventual accumulation was discussed, and dependences of experimental parameters on the accumulating position were evaluated as well. The particle concentration behavior can be classified into two types; one has similar accumulating characteristics in both gap patterns, the other is the case in which particles are concentrated at the center span of the channel. Consequently, it is indicated from the results in this study that an estimation of the particle concentration is possible in a device with more complicated electrode geometry based on that in the single-gap device. The particle focusing method by ACEO can contribute to an improvement of detection sensitivity in the microfluidic system.