Correlation between canal paresis and spontaneous nystagmus during early stage of acute peripheral vestibular disorders
Correlation between canal paresis and spontaneous nystagmus during early stage of acute peripheral vestibular disorders
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DOI：
10.3109/00016489.2010.497497
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发表时间：
2010-12-01
影响因子：
1.4
通讯作者：
Watanabe, Yukio
中科院分区：
文献类型：
--
作者：
Fushiki, Hiroaki;Ishida, Masayuki;Watanabe, Yukio
结论：这项研究表明，自发性眼球震颤（SN）的解决期可能提供一个指标的前庭功能障碍在特定的一天，在初级保健设置。目的：我们的目的是在急性周围性前庭疾病的早期阶段，使用SN的基本观察来预测神经管麻痹。研究方法：该研究涉及87名最近经历了首次急性自发性眩晕和方向固定水平眼震发作的患者。虽然他们没有表现出任何其他神经缺陷，但他们在2004年至2007年期间因严重的急性症状住院。综述了SN的分辨期与实验室冷热试验结果之间的相关性。结果如下：受试者操作特征分析表明，SN的消退时间可能是单侧前庭功能减退急性期的预测指标。在大约一半的患者中，SN在首次访视后第三天消失。然而，在20%的患者中，SN在第8天仍持续存在。在SN患者中，随着SN消退时间的增加，椎管麻痹的患病率增加。当在第5天观察到SN时，患病率约为70%。
Conclusions: This study demonstrates that the resolution period of spontaneous nystagmus (SN) may provide an indication of vestibular dysfunction on a particular day in the primary care setting. Objective: We aimed to predict canal paresis using fundamental observations of SN during the early stage of acute peripheral vestibular disorders. Methods: The study involved 87 patients who had recently experienced their first episode of acute spontaneous vertigo and direction-fixed horizontal nystagmus. Although they did not exhibit any other neurological deficits, they had been hospitalized with severe acute symptoms between 2004 and 2007. A correlation between the resolution period of SN and the results of laboratory caloric testing was reviewed. Results: The receiver operating characteristic analysis showed that the resolution period of SN may be a predictive indicator of unilateral vestibular hypofunction in the acute stage. In about half of the patients, SN disappeared on the third day after their initial visit. However, in 20% of the patients SN still persisted on the eighth day. Among the patients with SN, the prevalence of canal paresis increased with the increase in the resolution period of SN. When SN was observed on the fifth day, the prevalence was approximately 70%.