Bordetella parapertussis outbreak in Bisham, Pakistan in 2009-2010: fallout of the 9/11 syndrome
Bordetella parapertussis outbreak in Bisham, Pakistan in 2009-2010: fallout of the 9/11 syndrome
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DOI：
10.1017/s0950268814003732
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发表时间：
2015-09-01
影响因子：
4.2
通讯作者：
Bokhari, H.
中科院分区：
文献类型：
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作者：
Javed, S.;Said, F.;Bokhari, H.
百日咳是一种高度接触性的社区传染病，主要由百日咳杆菌和B类杆菌引起。副百日咳。我们报告了巴基斯坦开伯尔-普赫图恩卡瓦省斯瓦特附近的比舍姆的一次轻微百日咳暴发（2009-2010年）。有趣的是，我们的结果显示，所有从儿童（平均年龄3.46岁）收集的培养阳性分离株（n = 21）均被鉴定为B。在常规鉴定试验和PCR IS 481、IS 1001和IS 1002后，此外，在受影响的病人中，没有人接受过白喉-百日咳-破伤风疫苗的免疫接种。因此，还审查了由于9/11事件造成的政治动荡而限制基本卫生服务导致疾病重新出现的可能性。此外，我们还讨论了为成人和儿童接种含有这两种微生物的DTPwPaw疫苗以获得更好保护的重要性。
Pertussis or whooping cough is a highly contagious community disease mainly caused by Bordetella pertussis and B. parapertussis. We report a minor outbreak of whooping cough (2009-2010) in symptomatic subjects from Bisham, near Swat, Khyber Pukhtoonkhawa province, Pakistan. Interestingly, our results show that all the culture-positive isolates (n = 21) collected from children (average age 3.46 years), were identified as B. parapertussis after routine identification tests and PCR IS481, IS1001 and IS1002. Furthermore, in the affected patients, none had received immunization with diphtheria-pertussis-tetanus (DTPw) vaccine. Therefore, the possibility of the re-emergence of the disease due to limitation of basic health services as a result of the political unrest due to the 9/11 situation is also examined. Moreover, we discuss the importance of vaccinating both adults and children with DTPwPaw vaccine containing both organisms for better protection.