beta(1)-adrenoceptor autoimmunity in cardiomyopathy
beta(1)-adrenoceptor autoimmunity in cardiomyopathy
复制标题
DOI：
10.1016/0167-5273(96)02590-9
复制
发表时间：
1996-05-01
影响因子：
3.5
通讯作者：
Hoebeke, J
中科院分区：
文献类型：
--
作者：
Magnusson, Y;Hjalmarson, A;Hoebeke, J
越来越多的研究证实，针对β（1）-肾上腺素受体的自身抗体存在于不同类型的心肌病中。这表明它们在疾病的病理生理学中起作用。本文将综述抗β（1）肾上腺素受体自身抗体在心肌病中的存在。它将集中在他们的结构和功能特性，可以解释他们在心肌病的诱导和发展的可能作用。
A growing body of studies have confirmed that autoantibodies against beta(1)-adrenoceptors are present in different types of cardiomyopathy. This suggests that they play a role in the pathophysiology of the disease. This article will review the data indicating the presence of anti-beta(1)-adrenoceptor autoantibodies in cardiomyopathy. It will focus upon their structural and functional properties which could explain their possible role in the induction and development of cardiomyopathic diseases.