IN-VIVO AND IN-VITRO TESTING OF MICROELECTRONICALLY FABRICATED PLANAR SENSORS DESIGNED FOR APPLICATIONS IN CARDIOLOGY
IN-VIVO AND IN-VITRO TESTING OF MICROELECTRONICALLY FABRICATED PLANAR SENSORS DESIGNED FOR APPLICATIONS IN CARDIOLOGY
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DOI：
10.1007/bf00321250
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发表时间：
1993-06-01
期刊：
影响因子：
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通讯作者：
BUCK, RP
中科院分区：
文献类型：
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作者：
LINDNER, E;COSOFRET, VV;BUCK, RP
离子敏感的平面微电极阵列是通过光刻微电子技术在柔性聚酰亚胺基板上制造的。总结了微电子加工的步骤。电极在血清、全血和麻醉兔子的腿筋肌肉中进行了测试。将平面 pH 传感器的性能特征与商用玻璃电极进行了比较。数据的密切相关性对于进一步的急性和后来的慢性应用是令人鼓舞的。
Ion-sensitive, planar micro-electrode arrays were fabricated by photolithographic microelectronics technology on a flexible polyimide substrate. The steps of the microelectronics processing are summarized. The electrodes were tested in blood serum, whole blood and in the hamstring muscle of anesthetized rabbits. The performance characteristics of planar pH-sensors are compared with commercial glass electrodes. The close correlation of the data are encouraging for further acute and later chronic applications.