THE CONCENTRATION OF EPIDERMAL GROWTH-FACTOR IN JAPANESE MOTHERS MILK
THE CONCENTRATION OF EPIDERMAL GROWTH-FACTOR IN JAPANESE MOTHERS MILK
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DOI：
10.3177/jnsv.41.241
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发表时间：
1995-04-01
影响因子：
1.6
通讯作者：
IDOTA, T
中科院分区：
文献类型：
--
作者：
MATSUOKA, Y;IDOTA, T
用放射受体分析法（RRA）测定人乳中表皮生长因子（EGF）的含量。根据哺乳期、季节和居住地的不同，将从足月分娩的健康日本母亲中收集的母乳样本分为30组。冬季和夏季产后3 ~ 5天母乳中EGF含量分别为15.03 μ g/100 ml和15.46 μ g/100 ml。从31天到60天，牛奶中的浓度迅速下降至8.04微克/100毫升和8.12微克/100毫升，从241天到481天，牛奶中的浓度迅速下降至5.10微克/100毫升和5.44微克/100毫升。EGF浓度的季节性和区域性差异在一定程度上被观察到，但没有明确的趋势可以定义。这些结果表明，EGF是婴儿在分娩后早期阶段生长的重要和基本因素，因为它仅在哺乳开始时较高，然后下降。
The concentration of epidermal growth factor (EGF) in human milk was measured by radioreceptor assay (RRA). Human milk samples collected from healthy Japanese mothers who delivered at full term were divided into 30 groups according to differences in the duration of lactation, seasons of the year and place of residence. Human milk collected from 3 to 5 days after delivery in winter and summer contained 15.03 mu g/100 ml and 15.46 mu g/100 ml of EGF, respectively. The concentrations decreased rapidly to 8.04 mu g/100 ml and 8.12 mu g/100 ml in milk from 31 to 60 days, and to 5.10 mu g/100 ml and 5.44 mu g/100 ml in milk from 241 to 481 days. Seasonal and regional differences in EGF concentration were observed to some extent, but no clear tendency could be defined. These results suggest that EGF is an essential and fundamental factor for the growth of infants in the very early stages after delivery, because it was high only at the beginning of lactation and then it decreased.