Electrochemical and bio-sensing platform based on a novel 3D Cu nano-flowers/layered MoS2 composite
Electrochemical and bio-sensing platform based on a novel 3D Cu nano-flowers/layered MoS2 composite
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基于新型3D Cu纳米花/层状MoS2复合材料的电化学和生物传感平台
DOI：
10.1016/j.bios.2015.12.072
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发表时间：
2016
影响因子：
12.6
通讯作者：
Kokot Serge
中科院分区：
文献类型：
--
作者：
Lin Xiaoyun;Ni Yongnian;Kokot Serge
成功构建了一种新型三维纳米花状Cu/多层二硫化钼复合材料（CuNFs/MoS2）修饰的玻璃碳电极（GCE）。它是一种高度敏感和选择性的非酶促过氧化氢（H2O2）和葡萄糖生物传感器。利用扫描电子显微镜（SEM）、透射电子显微镜（TEM）、x射线衍射仪（XRD）和能谱仪（EDS）研究了所制得的cunfs - mos2纳米颗粒的形貌。利用电化学阻抗谱（EIS）和循环伏安法（CV）技术表征了修饰电极在每个构建阶段的物理化学性质。该传感器结合了mos2和CuNFs的优点，对h2o2和葡萄糖具有较高的电催化活性。采用电流法对h2o2和葡萄糖进行了定量分析。对h2o2的检测范围为0.04 ~ 1.88 μM和1.88 ~ 35.6 μM，对葡萄糖的检测范围为1 ~ 20 μM和20 ~ 70 μM，检出限分别为0.021 μM和0.32 μM。该传感器已成功应用于自来水中h2o2和人血清中葡萄糖的定量分析。
A novel 3D nano-flower-like Cu/multi-layer molybdenum disulfide composite (CuNFs/MoS2) modified glassy carbon electrode (GCE) has been successfully constructed. It was a highly sensitive and selective non-enzymatic hydrogen peroxide (H2O2) and glucose biosensor. The morphology of the obtained CuNFs-MoS2nano-particles was investigated with the use of a scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD) and energy dispersive X-ray spectroscopy (EDS). The physicochemical properties of the modified electrode were characterized at each of the construction stages with the use of an electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) techniques. The new sensor combined the advantages of MoS2and CuNFs, and exhibited high electro-catalytic activity toward H2O2and glucose. Quantitative analysis of H2O2and glucose was carried out with the use of the amperometrici–tmethod. Linear ranges were obtained between 0.04–1.88 μM and 1.88–35.6 μM for H2O2and 1–20 μM and 20–70 μM for glucose, and their corresponding limits of detection (LOD) were 0.021 μM and 0.32 μM. This novel sensor was successfully applied for the quantitative analysis of H2O2in tap water and glucose in human serum samples.