Mechanical control of enantioselectivity of amino acid recognition by cholesterol-armed cyclen monolayer at the air-water interface
Mechanical control of enantioselectivity of amino acid recognition by cholesterol-armed cyclen monolayer at the air-water interface
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DOI：
10.1021/ja066429t
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发表时间：
2006-11-15
影响因子：
15
通讯作者：
Ariga, Katsuhiko
中科院分区：
文献类型：
--
作者：
Michinobu, Tsuyoshi;Shinoda, Satoshi;Ariga, Katsuhiko
在空气−水界面上的胆固醇臂环素Na+复合体的单分子膜显示出显著的、依赖于表面压力的氨基酸识别的对映选择性。当压缩单分子膜时，氨基酸的结合常数增加，同时在Valine的情况下，手性选择性从Thed-tol-form反转。
Monolayers of the cholesterol-armed cyclen Na+complex at the air−water interface display a remarkable, surface pressure dependent enantioselectivity of amino acid recognition. Upon compression of the monolayer, the binding constants of amino acids increase accompanying an inversion of chiral selectivity from thed- tol-form in the case of valine.