Frontal absences in children.
Frontal absences in children.
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儿童额叶缺失。
DOI：
10.1053/ejpn.2001.0524
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发表时间：
2001
影响因子：
3.1
通讯作者：
J. Vervisch
中科院分区：
文献类型：
--
作者：
L. Lagae;J. Pauwels;CP Monté;B. Verhelle;J. Vervisch
在一个队列的59个连续的儿童提到的凝视法术，我们分析了临床和脑电图（EEG）的特点，在23名儿童的历史，失神发作和广义的尖峰和波模式，在长期的视频脑电图监测。在10名儿童中，额叶锋电位先于广义锋电位和波型。其余13例患儿均可见原发性全身性棘波和波，额部发作的失神与原发性全身性失神在临床上无差异。两组之间最显著的区别是，额叶发作组难以控制缺席，该组的学习和行为问题发生率很高。脑电图分析显示，发作间期，孤立的癫痫放电在80%的儿童额叶发作的缺席。我们认为，额叶发作的缺失应被视为继发性全身性癫痫综合征，起源于额叶地区。
In a cohort of 59 consecutive children referred for staring spells, we analysed clinical and electroencephalogram (EEG) characteristics in 23 children with both a history of absence seizures and a generalized spike and wave pattern during long-term video EEG monitoring. In 10 children, a frontal spike preceded the generalized spike and wave pattern. In the remaining 13 children, primary generalized spikes and waves were found. The frontal onset absences were clinically not different from primary generalized absences. The most striking difference between the two groups was the difficulty in controlling the absences in the frontal onset group and the high incidence of learning and behavioural problems in that group. The EEG analysis showed interictal, isolated epileptic discharges in 80% of the children with frontal onset absences. We believe that frontal onset absences should be considered as a secondarily generalized epilepsy syndrome, originating in the frontal regions.