Kidney size at diagnosis of childhood acute lymphocytic leukemia: lack of prognostic significance for outcome.
Kidney size at diagnosis of childhood acute lymphocytic leukemia: lack of prognostic significance for outcome.
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儿童急性淋巴细胞白血病诊断时的肾脏大小：对结果缺乏预后意义。
DOI：
10.1097/00043426-198824000-00005
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
NesbitJr,ME
中科院分区：
文献类型：
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作者：
Neglia,JP;Day,DL;Swanson,TV;Ramsay,NK;Robison,LL;NesbitJr,ME
在142名儿童中评估了肾脏大小在诊断急性淋巴细胞白血病（ALL）时的预后意义。使用三种不同的方法确定肾脏大小，并通过单变量和多变量生命表方法确定其显着性。肾脏增大（通过三种方法中的任何一种确定）与总体生存率降低无关。当诊断时的肾脏大小作为单一变量进行分析时，以及在校正年龄、性别和初始WBC计数等已知预后因素后考虑时，这些结果是一致的。在诊断儿童ALL时评估肾脏大小不适用于预测随后的预后。
The prognostic significance of kidney size at diagnosis of acute lymphoblastic leukemia (ALL) was assessed in a population of 142 children. Kidney size was determined using three different methodologies, and its significance was determined by univariate and multivariate life-table methods. Enlarged kidney size (as determined by any of the three methods used) was not associated with an overall poorer survival. These findings were consistent when kidney size at diagnosis was analyzed as a singled variable and when it was considered after adjustment for the known prognostic factors of age, sex, and initial WBC count. Assessment of renal size at the time of diagnosis of childhood ALL is not indicated for the purpose of predicting subsequent prognosis.