Multi-institutional analysis of long-term symptom resolution after cholecystectomy for biliary dyskinesia in children
Multi-institutional analysis of long-term symptom resolution after cholecystectomy for biliary dyskinesia in children
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儿童胆道运动障碍胆囊切除术后长期症状缓解的多机构分析
DOI：
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发表时间：
2013
期刊：
影响因子：
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通讯作者：
K. Azarow
中科院分区：
文献类型：
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作者：
E. Knott;F. Fike;A. Gasior;R. Cusick;E. Brownie;S. S. St. Peter;K. Azarow
目的：目前关于胆道运动障碍儿童胆囊切除术后腹痛缓解的文献显示了不同的结局。我们试图比较儿童的早期结果与长期症状解决情况。方法对2000年1月至2011年1月期间在两个中心因胆道运动障碍接受胆囊切除术的儿童进行电话调查。进行回顾性分析，以获得人口统计学和短期outcomes.Results105例患者的年龄7.9-19岁的图表进行了审查，80.9%是女性。所有患者均有射血分数（EF）<35%或胆囊收缩素给药疼痛的症状.术后随访时，76.1%的患者症状缓解。五十六例（53.3%）患者可接受中位随访3.7（1.1-10.7）年。其中，34例（60.7%）报告无持续腹痛。22例症状持续的患者中，满意度评分为7.3 ± 2.7（1-10分），19例（86.4%）对他们进行胆囊切除术感到高兴。EF，体重指数百分位数（BMI %），并与胆囊收缩素（CCK）的疼痛没有预测持续的疼痛，在任何后续periods.ConclusionShort-term症状的解决在儿童接受胆囊切除术的胆道运动障碍是不反映长期的结果。EF、BMI %和CCK疼痛均不能预测症状缓解。大多数持续主诉的患者不后悔胆囊切除术。
PurposeCurrent literature for resolution of abdominal pain after cholecystectomy in children with biliary dyskinesia shows variable outcomes. We sought to compare early outcomes with long-term symptom resolution in children.MethodsTelephone surveys were conducted on children who underwent cholecystectomy for biliary dyskinesia between January 2000 and January 2011 at two centers. Retrospective review was performed to obtain demographics and short-term outcomes.ResultsCharts of 105 patients’ age 7.9–19 years were reviewed; 80.9 % were female. All were symptomatic with an ejection fraction (EF) <35 % or pain with cholecystokinin administration. At the postoperative visit, 76.1 % had resolution of symptoms. Fifty-six (53.3 %) patients were available for follow-up at median 3.7 (1.1–10.7) years. Of these, 34 (60.7 %) reported no ongoing abdominal pain. Of the 22 patients with persistent symptoms, satisfaction score was 7.3 ± 2.7 (scale of 1–10) and 19 (86.4 %) were glad that they had a cholecystectomy performed. EF, body mass index percentile (BMI %), and pain with cholecystokinin (CCK) were not predictive of ongoing pain at either follow-up periods.ConclusionShort-term symptom resolution in children undergoing cholecystectomy for biliary dyskinesia is not reflective of long-term results. Neither EF, BMI % nor pain with CCK was predictive of symptom resolution. The majority of patients with ongoing complaints do not regret cholecystectomy.