Prepregnancy obesity predicts poor vitamin D status in mothers and their neonates
Prepregnancy obesity predicts poor vitamin D status in mothers and their neonates
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DOI：
10.1093/jn/137.11.2437
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发表时间：
2007-11-01
影响因子：
4.2
通讯作者：
Simhan, Hyagriv N.
中科院分区：
文献类型：
--
作者：
Bodnar, Lisa M.;Catov, Janet M.;Simhan, Hyagriv N.
肥胖是维生素D缺乏的一个危险因素，但这种关系尚未在孕妇中进行研究，因为孕妇必须维持自己和胎儿的维生素D储备。我们的目的是评估孕前BMI对母亲和新生儿25-羟基维生素D [25（OH）D]浓度的影响。本文测定了200例白色和200例黑人孕妇孕4-21周及分娩前血清及新生儿脐血中25（OH）D的含量。我们使用多变量逻辑回归模型来评估BMI和维生素D缺乏[25（OH）D]几率之间的独立关联
Obesity is a risk factor for vitamin D deficiency, but this relation has not been studied among pregnant women, who must sustain their own vitamin D stores as well as those of their fetuses. Our objective was to assess the effect of prepregnancy BMI on maternal and newborn 25-hydroxyvitamin D [25(OH)D] concentrations. Serum 25(OH)D was measured at 4-21 wk gestation and predelivery in 200 white and 200 black pregnant women and in their neonates' cord blood. We used multivariable logistic regression models to assess the independent association between BMI and the odds of vitamin D deficiency [25(OH)D