Cyclic neutropenia: A tale of two brothers and their family
Cyclic neutropenia: A tale of two brothers and their family
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周期性中性粒细胞减少症：两兄弟及其家人的故事
DOI：
10.1097/00043426-198100320-00003
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
J. B. Jones
中科院分区：
文献类型：
--
作者：
R. Lange;C. Crowder;P. Cruz;S. Hawkinson;C. Lozzio;E. Machado;P. Painter;W. Terry;J. B. Jones
介绍了一部包含四代人的家族史。明确的周期性中性粒细胞减少症已在两代人中被注意到。在一名成员中，随着年龄的增长，症状有所减轻。1例12岁患儿死于回肠末端坏疽继发的梭状芽胞杆菌败血症。尸检发现他患有淀粉样变性。对一名7岁男性进行了碳酸锂治疗的试验，但血液学没有得到阳性反应。
A family history encompassing four generations is presented. Definite cyclic neutropenia has been noted in two generations. In one member, the symptoms abated as she grew older. One 12-year-old member died of clostridial septicemia secondary to gangrene of the terminal ileum. At autopsy he was found to have amyloidosis. A trial of lithium carbonate therapy was carried out in a 7-year-old male but a positive hematologic response was not obtained.