Determinants in early life for asthma development.
Determinants in early life for asthma development.
复制标题
DOI：
10.1186/1710-1492-5-6
复制
发表时间：
2009-11-09
期刊：
影响因子：
--
通讯作者：
Van Bever HP
中科院分区：
文献类型：
--
作者：
Van Bever HP
一个可靠的筛选试验，在新生儿随后的发展支气管哮喘（BA）尚未发现。这主要是由于BA的复杂性，由不同类型和潜在机制组成。在不同的研究中，已经确定了许多BA的风险因素。这些因素包括BA阳性家族史、被动吸烟（也包括妊娠期间）、早产（包括肺部感染、RDS和BPD）、早期病毒性呼吸道感染（如RSV-细支气管炎）、男性、早期肺功能异常和特应性体质。持续性BA的主要危险因素是潜在的过敏体质。因此，过敏的早期症状和标志物（即过敏性三月）和过敏的阳性家族史应被认为是BA发展的重要危险因素。
A reliable screening test in newborns for the subsequent development of bronchial asthma (BA) has not been found yet. This is mainly due to the complexity of BA, being made up by different types and underlying mechanisms. In different studies, a number of risk factors for BA have been identified. These include a positive family history of BA, passive smoking (also during pregnancy), prematurity (including pulmonary infections, RDS and BPD), early viral respiratory infections (such as RSV-bronchiolitis), male gender, early lung function abnormalities and atopic constitution. The major risk factor for persistent BA is an underlying allergic constitution. Therefore, early symptoms and markers of allergy (i.e. The Allergic March) and a positive family history for allergy should be considered as important risk factors for the development of BA.