Preventing Hypoglycemia Using Predictive Alarm Algorithms and Insulin Pump Suspension
Preventing Hypoglycemia Using Predictive Alarm Algorithms and Insulin Pump Suspension
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DOI：
10.1089/dia.2008.0032
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发表时间：
2009-02-01
影响因子：
5.4
通讯作者：
Chase, H. Peter
中科院分区：
文献类型：
--
作者：
Buckingham, Bruce;Cobry, Erin;Chase, H. Peter
背景：夜间低血糖是一个重要的问题。50%至75%的低血糖发作发生在夜间。尽管带有降糖报警器的实时血糖传感器(实时连续血糖监测仪[CGM])已经开发出来，但许多患者还是通过这些报警器睡觉。这项先导性研究的目的是评估在预测低血糖时使用实时CGM停止胰岛素泵治疗的可行性。方法：22名1型糖尿病患者在临床研究中心有两次日间入院。在第一次入院时，他们的基础胰岛素会增加，直到他们的血糖水平达到
Background: Nocturnal hypoglycemia is a significant problem. From 50% to 75% of hypoglycemia seizures occur at night. Despite the development of real-time glucose sensors (real-time continuous glucose monitor [CGM]) with hypoglycemic alarms, many patients sleep through these alarms. The goal of this pilot study was to assess the feasibility using a real-time CGM to discontinue insulin pump therapy when hypoglycemia was predicted.Methods: Twenty-two subjects with type 1 diabetes had two daytime admissions to a clinical research center. On the first admission their basal insulin was increased until their blood glucose level was