NASAL CONSTANT POSITIVE AIRWAY PRESSURE INHIBITS THE SWALLOWING REFLEX
NASAL CONSTANT POSITIVE AIRWAY PRESSURE INHIBITS THE SWALLOWING REFLEX
复制标题
DOI：
10.1164/ajrccm/140.5.1290
复制
发表时间：
1989-11-01
期刊：
影响因子：
--
通讯作者：
HIRAGA, K
中科院分区：
文献类型：
--
作者：
NISHINO, T;SUGIMORI, K;HIRAGA, K
本文对8名成人进行了鼻罩鼻压造影剂对吞咽反射的影响。在4种不同的气道呼气压力值（0、5、10、15 cm H2O CPAP）下，将少量蒸馏水（0.5 ml）在咽内注射，或在2种不同的气道呼气压力值（0、15 cm H2O CPAP）下连续输水（3 ml/min），诱导吞咽反射。测定了从注射水开始到第一个燕子出现的反应潜伏期，以及注射水后10 s内引起的燕子数量。我们的研究结果表明，气道呼气压力的增加逐渐延长了反应的潜伏期，并减少了吞咽的次数。在持续输水15 cm H2O的鼻腔CPAP下，吞咽次数明显减少。这些结果表明鼻腔CPAP对吞咽反射有抑制作用。
The effects of contrast positive airway pressure applied via a nose mask through the nares (nasal CPAP) on the swallowing reflex were studied in eight adult humans. The swallowing reflex was induced by bolus injections of a small amount of distilled water (0.5 ml) into the pharynx at four different values of endexpiratory airway pressure (0, 5, 10, and 15 cm H2O CPAP) or by continuous infusion of water (3 ml/min) at two different values of endexpiratory airway pressure (0 and 15 cm H2O CPAP). The latency of response from the time of bolus injection of water to the occurence of the first swallow as well as the number of swallows elicted during the period of 10 s immediately following the water injection were measured. Our results showed that increases in endexpiratory airway pressure progressively prolonged the latency of response and decreased the number of swallows. Also, the frequency of swallows decreased greatly at nasal CPAP of 15 cm H2O during continuous infusion of water. These results indicate that nasal CPAP exerts an inhibitory influence on the swallowing reflex.