Falls: descriptive rates and circumstances in age-unspecified patients with locally advanced esophageal cancer.
Falls: descriptive rates and circumstances in age-unspecified patients with locally advanced esophageal cancer.
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DOI：
10.1007/s00520-020-05511-z
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发表时间：
2021-03
期刊：
影响因子：
--
通讯作者：
Jatoi A
中科院分区：
文献类型：
--
作者：
Childs DS;Yoon HH;Eiring RA;Jin Z;Jochum JA;Pitot HC;Jatoi A
老年癌症患者也可能摔倒，但很少有研究对年龄不详的局部晚期食管癌患者摔倒进行调查。由于这些患者经常使用神经病变诱导药物，身体虚弱，并可能出现直立性症状，因此检查跌倒似乎是相关的。电子医疗记录用于检查局部晚期食管癌患者的跌倒及其情况，这些患者接受了化疗和放疗，通常还进行了手术。在300例患者中，62例（21%）发生跌倒，每100例患者年发生6次跌倒。首次跌倒的中位年龄为64岁（31至83岁）。从癌症诊断到首次跌倒的中位时间为11个月（范围0 - 107）。42名患者（68%）患有活动性癌症；20例（32%）无癌。42例患者发生跌倒相关损伤，包括骨折、血肿和其他肌肉骨骼事件。18例（29%）反复跌倒。神经病变、全身无力和直立症状与跌倒有关(“他确实说他的神经病变更麻烦。他上周确实摔了一跤“ ”他身体越来越虚弱，以至于上周摔倒了。“一站起来，他就觉得好像有人用床单盖住了他的眼睛，感到头晕目眩，然后倒在了地板上。”……”)。有时，在常见的情况下也会摔倒，比如在冰上滑倒或被脚下的宠物绊倒。无论患者年龄如何，临床医生都应该对局部晚期食管癌成年患者的跌倒风险保持警惕。
Falls can occur in older cancer patients, but few studies have examined falls in an age-unspecified group of patients with locally advanced esophageal cancer. Because these patients are often administered neuropathy-inducing agents, are weak, and can develop orthostatic symptoms, examining falls appears relevant. Electronic medical records were used to examine falls and their circumstances in locally advanced esophageal cancer patients treated with chemotherapy and radiation and often surgery. Among 300 patients, 62 (21%) suffered a fall, yielding 6 falls per 100 patient years. The median age at first fall was 64 years (range 31 to 83). The median time from cancer diagnosis to first fall was 11 months (range 0 to 107). Forty-two patients (68%) who fell had active cancer; 20 (32%) were cancer-free. Fall-related injuries occurred in 42 patients and included fractures, hematomas, and other musculoskeletal events. Eighteen patients (29%) fell repeatedly. Neuropathy, general weakness, and orthostatic symptoms were associated with falls (“He does state his neuropathy is more bothersome.… He did have a fall last week ” “He has been increasingly weak to the point where he fell down last week.…” “Upon rising… [he] felt like somebody had put a sheet over his eyes, felt very lightheaded, and fell to the floor. …”). At times, falls occurred under commonplace circumstances, such as slipping on ice or tripping on an underfoot pet. Regardless of patient age, clinicians should remain vigilant for fall risk in adult patients with locally advanced esophageal cancer.
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影响因子：
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作者：
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影响因子：
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作者：
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