Neonatal seizures. I. Correlation of prenatal and perinatal events with outcomes.
Neonatal seizures. I. Correlation of prenatal and perinatal events with outcomes.
复制标题
新生儿惊厥。
作者：
Holden Kr;E. Mellits;J. Freeman
对参与围产期合作项目的277例新生儿癫痫发作的回顾显示死亡率为34.8%。在181名幸存者中，大多数随访至7岁，70%正常。因此，尽管癫痫发作是围产期窒息的主要指标，也是随后神经功能缺陷的预测指标，但大多数新生儿癫痫发作存活下来的婴儿都表现良好。13%的人患有脑瘫，19%的人智商低于70,20%的人患有癫痫。13%的幸存者同时患有智力迟钝、脑瘫或癫痫。低Apgar评分、5分钟后需要复苏、低出生体重、早发性癫痫发作或长时间癫痫发作与不良结局相关。
A review of 277 newborns with neonatal seizures enrolled in the Collaborative Perinatal Project revealed a mortality of 34.8%. Of the 181 survivors, most followed up to age 7 years, 70% were normal. Thus, despite the fact that seizures are a major indicator of perinatal asphyxia and a predictor of subsequent neurologic deficit, most infants with neonatal seizures who survived did well. Thirteen percent had cerebral palsy, 19% had an IQ less than 70, and 20% had epilepsy. Thirteen percent of survivors had a combination of mental retardation, cerebral palsy, or epilepsy. A low Apgar score, the need for resuscitation after 5 minutes of age, low birth weight, and the early onset of seizures or prolonged seizures correlated with adverse outcome.