Global Analysis of Multitrial Data Investigating Quality of Life and Symptoms as Prognostic Factors for Survival in Different Tumor Sites

Global Analysis of Multitrial Data Investigating Quality of Life and Symptoms as Prognostic Factors for Survival in Different Tumor Sites
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DOI:
10.1002/cncr.28382
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发表时间:
2014-01-15
期刊:
影响因子:
6.2
通讯作者:
Bottomley, Andrew
Bottomley, Andrew
中科院分区:
医学1区
文献类型:
--
作者:
Quinten, Chantal;Martinelli, Francesca;Bottomley, Andrew

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BACKGROUNDThe objective of this study was to examine the prognostic value of baseline health-related quality of life (HRQOL) for survival with regard to different cancer sites using 1 standardized and validated patient self-assessment tool.METHODSIn total, 11 different cancer sites pooled from 30 European Organization for Research and Treatment of Cancer (EORTC) randomized controlled trials were selected for this study. For each cancer site, univariate and multivariate Cox proportional hazards modeling was used to assess the prognostic value (P