Effectiveness of mRNA COVID-19 vaccines in preventing SARS-CoV-2 infections and COVID-19 hospitalisations and deaths in elderly long-term care facility residents, Spain, weeks 53 2020 to 13 2021.

Effectiveness of mRNA COVID-19 vaccines in preventing SARS-CoV-2 infections and COVID-19 hospitalisations and deaths in elderly long-term care facility residents, Spain, weeks 53 2020 to 13 2021.
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DOI：
10.2807/1560-7917.es.2021.26.24.2100452
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发表时间：
2021-06
期刊：
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
影响因子：
--
通讯作者：
Working group for the surveillance and control of COVID-19 in Spain
Working group for the surveillance and control of COVID-19 in Spain
中科院分区：
其他
文献类型：
--
作者：
Mazagatos C;Monge S;Olmedo C;Vega L;Gallego P;Martín-Merino E;Sierra MJ;Limia A;Larrauri A;Working Group for the surveillance and control of COVID-19 in Spain;Working group for the surveillance and control of COVID-19 in Spain
来源链接：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212595/

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在西班牙2019冠状病毒病大流行期间，长期护理机构（LTCF）的居民发病率和死亡率很高，并优先获得早期COVID-19疫苗接种。我们使用筛选方法和基于人群的数据源来估计老年LTCF居民的mRNA COVID-19疫苗有效性。对SARS-CoV-2感染（有症状和无症状）和COVID-19住院和死亡的估计分别为71% （95% CI: 56-82%）、88% （95% CI: 75-95%）和97% （95% CI: 92-99%）。
Residents in long-term care facilities (LTCF) experienced a large morbidity and mortality during the COVID-19 pandemic in Spain and were prioritised for early COVID-19 vaccination. We used the screening method and population-based data sources to obtain estimates of mRNA COVID-19 vaccine effectiveness for elderly LTCF residents. The estimates were 71% (95% CI: 56–82%), 88% (95% CI: 75–95%), and 97% (95% CI: 92-99%), against SARS-CoV-2 infections (symptomatic and asymptomatic), and COVID-19 hospitalisations and deaths, respectively.