Neurospora Mutant Lacking an Arginine-Specific Carbamyl Phosphokinase
Neurospora Mutant Lacking an Arginine-Specific Carbamyl Phosphokinase
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DOI：
10.1126/science.142.3600.1652
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发表时间：
1963-12
期刊：
影响因子：
56.9
通讯作者：
Rowland H. Davis
中科院分区：
文献类型：
--
作者：
Rowland H. Davis
脉孢菌属的一种需要精氨酸的突变体缺乏存在于其他菌株中的氨甲酰磷酸激酶活性。虽然氨甲酰磷酸，这种酶的产物，在精氨酸和嘧啶合成中都是必需的，但这种酶似乎只在精氨酸途径中起作用。一个嘧啶特定模式的氨甲酰磷酸合成的推断，虽然它还没有被证明。
An arginine-requiring mutant of Neurospora lacks the carbamyl phosphokinase activity present in other strains. Although carbamyl phosphate, the product of this enzyme, is required in both arginine and pyrimidine synthesis, the enzymne appears to serve only the arginine pathway. A pyrimidine specific mode of carbamyl phosphate synthesis is inferred, although it has not yet been demonstrated.